1 00:00:06,612 --> 00:00:09,740 All right, hold on. I got the turn up here. 2 00:00:10,824 --> 00:00:12,200 (WHOOPING) 3 00:00:17,789 --> 00:00:20,459 Oh! How cool was that? 4 00:00:20,584 --> 00:00:22,336 That was way cool! 5 00:00:26,757 --> 00:00:29,176 - My turn. - Sorry, that's not allowed. 6 00:00:29,301 --> 00:00:31,094 I just signed 15 pages of forms saying 7 00:00:31,219 --> 00:00:34,306 - you gotta rideon the back. - I don't see any lawyers around. 8 00:00:34,431 --> 00:00:36,391 - You know that's not the point. - No. 9 00:00:36,516 --> 00:00:39,394 You just wanna keep all the fun to yourself. 10 00:00:40,437 --> 00:00:41,813 Come on, Dad! 11 00:00:42,939 --> 00:00:45,275 You go over 15, we're pulling over, all right? I mean it. 12 00:00:45,400 --> 00:00:47,736 - You're the best. - All right, get on there. 13 00:00:47,861 --> 00:00:49,946 - Put on your goggles. - Okay. 14 00:00:50,864 --> 00:00:52,908 - Ready? - Got the clutch in? 15 00:00:53,033 --> 00:00:55,035 All right, that's my boy. 16 00:00:57,746 --> 00:00:59,915 (WHOOPING) 17 00:01:08,799 --> 00:01:11,593 Adam, you're going too fast, slow it down! 18 00:01:14,763 --> 00:01:17,766 I mean it, you're going too fast. Slow down! 19 00:01:17,891 --> 00:01:19,184 Adam! 20 00:01:24,314 --> 00:01:25,440 Adam! 21 00:01:27,234 --> 00:01:29,111 Let go of the throttle! 22 00:01:33,407 --> 00:01:34,324 Adam! 23 00:01:34,783 --> 00:01:36,535 Adam! No! 24 00:02:11,903 --> 00:02:14,531 PARAMEDIC: What've you got? Sixteen-year-old, status post, 25 00:02:14,656 --> 00:02:16,450 ATV crash, 40% burns on his body. 26 00:02:16,742 --> 00:02:17,993 Nasotracheal intubation. 27 00:02:18,118 --> 00:02:19,995 Start a bag of lactated Ringer's, wide open... 28 00:02:20,120 --> 00:02:22,080 - Will he be okay? - We'll be with you when we can. 29 00:02:22,205 --> 00:02:23,665 Get him out! 30 00:02:23,874 --> 00:02:25,667 Wait, wait, wait! 31 00:02:25,959 --> 00:02:28,837 NURSE: I'll start fluids. Let's go get him hooked up. 32 00:02:30,630 --> 00:02:32,090 SURGEON: Watch the line. 33 00:02:43,894 --> 00:02:45,520 (READING HINDI) 34 00:02:50,734 --> 00:02:53,779 - Been looking for you. - Been avoiding you. 35 00:02:53,904 --> 00:02:54,988 Burn Unit can handle it. 36 00:02:55,113 --> 00:02:58,784 If they could handle it, they wouldn't be asking for you. 37 00:03:00,619 --> 00:03:02,746 - Is that a journal? - Friend wrote an article. 38 00:03:02,871 --> 00:03:04,039 In Hindi? 39 00:03:04,164 --> 00:03:07,417 They have a cutting-edge neuroscience program in India. 40 00:03:07,542 --> 00:03:09,795 It says so right on the cover. 41 00:03:13,590 --> 00:03:15,759 Kid's heart rate's messed. 42 00:03:15,884 --> 00:03:18,053 Tachycardia can be explained by the burn. 43 00:03:18,178 --> 00:03:20,680 I assume the Burn Unit knew that. 44 00:03:22,849 --> 00:03:24,726 His potassium's low. 45 00:03:24,851 --> 00:03:26,728 Which can also be explained by the burn. 46 00:03:26,853 --> 00:03:29,231 Except I'm sure the Burn Unit's pumping him with fluids 47 00:03:29,356 --> 00:03:31,817 which means his potassium should be going up, not down. 48 00:03:31,942 --> 00:03:33,610 Could be amphetamines. 49 00:03:33,735 --> 00:03:35,529 Or bacteria lunching on his heart. 50 00:03:35,654 --> 00:03:38,782 Or cardiomyopathy, or some other very bad thing. 51 00:03:38,907 --> 00:03:40,659 HOUSE: He needs an EKG. 52 00:03:42,744 --> 00:03:43,745 (EXCLAIMING) 53 00:03:47,624 --> 00:03:50,794 Okay, no skin, no EKG. 54 00:03:50,919 --> 00:03:53,171 CHASE: Is he even gonna survive the burn? 55 00:03:53,380 --> 00:03:55,549 What, you got a date or something? 56 00:03:55,924 --> 00:03:58,134 Forty percent of his body. 57 00:03:58,260 --> 00:04:00,804 If the Burns Unit can prevent an infection, 58 00:04:00,929 --> 00:04:02,806 his body will regenerate maybe 10%, 59 00:04:02,931 --> 00:04:05,851 surgeons will do 20 or so grafts, six months in this room, 60 00:04:05,976 --> 00:04:09,396 he'll end up with a series of nasty scars, maybe some pain, 61 00:04:09,521 --> 00:04:10,730 but he'll live. 62 00:04:11,481 --> 00:04:12,732 Unless his heart shuts down 63 00:04:12,858 --> 00:04:17,571 'cause we can't figure cut what's causing the low potassium and tachycardia. 64 00:04:18,321 --> 00:04:21,658 We need help from a Belgian doc named Einthoven. 65 00:04:21,783 --> 00:04:23,076 He's dead. 66 00:04:23,201 --> 00:04:26,997 While he was alive, he invented a little dittie called the Galvanometer. 67 00:04:27,122 --> 00:04:28,164 Where do we get one? 68 00:04:28,290 --> 00:04:31,960 Go to any electronics store that's been open since before 1905. 69 00:04:32,085 --> 00:04:35,881 There's a good chance they've got one in a corner in the basement. 70 00:04:37,257 --> 00:04:39,801 BRENDA: We need an audio-visual setup for the lecture hall. 71 00:04:39,926 --> 00:04:41,803 - What for? - For the lecture. 72 00:04:41,928 --> 00:04:44,264 - What lecture? - Dr. Weber's lecture. 73 00:04:44,556 --> 00:04:47,976 - Who is Dr. Weber? - A neurologist, I think. 74 00:04:48,518 --> 00:04:50,395 The memo was from you. 75 00:04:56,818 --> 00:04:58,904 - Where is my assistant? - She left. 76 00:04:59,029 --> 00:05:00,196 - When? - Wednesday. 77 00:05:00,322 --> 00:05:02,741 - Seriously? - Well, the temp agency sent someone, 78 00:05:02,866 --> 00:05:03,909 but she got lost. 79 00:05:04,034 --> 00:05:06,620 Well, when she gets here, fire her. 80 00:05:27,140 --> 00:05:28,934 Oh, yeah. 81 00:05:29,059 --> 00:05:31,686 - Did you issue this memo? - Look at that. 82 00:05:33,605 --> 00:05:34,981 Congratulations. 83 00:05:35,106 --> 00:05:37,192 The patient that has been in a coma for two years and counting 84 00:05:37,317 --> 00:05:38,693 is still in a coma. 85 00:05:38,818 --> 00:05:40,153 This is not my signature. 86 00:05:40,278 --> 00:05:41,738 I don't know anything about this guy. 87 00:05:41,863 --> 00:05:44,658 I'm supposed to introduce him? Have lunch? 88 00:05:46,660 --> 00:05:49,496 - The coma patient has a migraine? - Oh, no, no, no. 89 00:05:49,621 --> 00:05:51,748 No, I gave him medication to prevent a migraine. 90 00:05:51,873 --> 00:05:53,416 That's a migraine. 91 00:05:53,541 --> 00:05:55,627 Increased flow velocity in his cerebral arteries. 92 00:05:55,752 --> 00:05:58,546 I did subsequently give him nitroglycerin, which could possibly... 93 00:05:58,672 --> 00:06:02,634 You induced a migraine headache in a coma patient? 94 00:06:02,759 --> 00:06:06,554 I gave him a little headache, similar to the one you're giving me now. 95 00:06:06,680 --> 00:06:09,099 Have you even read an ethical guideline? 96 00:06:09,224 --> 00:06:12,143 Well, it would be wrong to try out a new migraine prevention medication 97 00:06:12,268 --> 00:06:14,521 on someone who can actually feel pain. 98 00:06:14,646 --> 00:06:17,732 - Did you sign this? - Yeah. 99 00:06:19,025 --> 00:06:22,487 We can talk later about the appropriate discipline. 100 00:06:25,824 --> 00:06:26,950 CAMERON: Because of the burn, 101 00:06:27,075 --> 00:06:29,619 we can't perform any of our normal tests to see what's wrong. 102 00:06:29,744 --> 00:06:32,205 So we're going to try a Galvanometer. 103 00:06:32,789 --> 00:06:36,001 It picks up a pulse in the wrists and the ankles. 104 00:06:36,418 --> 00:06:39,671 Hopefully it'll tell us why his heart rhythm is abnorlnal. 105 00:06:39,796 --> 00:06:42,841 - What have I done to him? I... - It was an accident. 106 00:06:43,717 --> 00:06:45,218 All right? So... 107 00:06:46,136 --> 00:06:47,554 He's got all these burns 108 00:06:47,679 --> 00:06:49,639 and now there's something wrong with his heart? 109 00:06:49,764 --> 00:06:52,684 We're trying to figure out if the two are somehow connected. 110 00:06:52,809 --> 00:06:55,770 - Had he been sick lately? - No, nothing. 111 00:06:55,895 --> 00:06:57,397 Anything unusual with his behavior? 112 00:06:57,522 --> 00:06:59,107 - Had he been tired a lot? - Nothing. 113 00:06:59,232 --> 00:07:03,445 He was great, he was happy, he was just having a great time, and then... 114 00:07:03,570 --> 00:07:07,073 If he was experimenting with amphetamines or cocaine... 115 00:07:07,198 --> 00:07:08,241 No. 116 00:07:08,783 --> 00:07:11,703 We gave him some pot about a year ago, to try... 117 00:07:11,828 --> 00:07:13,204 It was just once. 118 00:07:13,329 --> 00:07:15,749 We thought if we took the mystery out of drugs and alcohol, 119 00:07:15,874 --> 00:07:17,250 the less he'd experiment. 120 00:07:17,375 --> 00:07:19,753 We'll know more after the tests. 121 00:07:21,629 --> 00:07:24,549 It looks like they're gonna electrocute him. 122 00:07:25,800 --> 00:07:27,052 Plug it in. 123 00:07:28,678 --> 00:07:30,096 You plug it in. 124 00:07:30,805 --> 00:07:32,724 Fine. Give me the cord. 125 00:07:39,606 --> 00:07:40,648 Works. 126 00:07:43,193 --> 00:07:44,736 Prominent U waves. 127 00:07:44,861 --> 00:07:47,697 No inverted T wave. No ischemia. 128 00:07:47,822 --> 00:07:49,491 Q wave normal. 129 00:07:50,366 --> 00:07:51,910 That's not good. 130 00:07:55,789 --> 00:07:57,957 Okay, turn it off. Turn it off! 131 00:07:58,083 --> 00:07:59,959 - What's happening? - What is that? 132 00:08:00,085 --> 00:08:01,419 CHASE: The seizure's getting... 133 00:08:01,544 --> 00:08:03,213 Can't you stop that? 134 00:08:10,386 --> 00:08:12,055 Who electrocuted my patient? 135 00:08:12,180 --> 00:08:14,057 - He had a seizure. - CAMERON: He wasn't electrocuted. 136 00:08:14,182 --> 00:08:16,726 What does the seizure tell us? Move. 137 00:08:16,851 --> 00:08:18,103 What are you looking for? 138 00:08:18,228 --> 00:08:21,898 Same as you are, love, acceptance, solid return on an investment. 139 00:08:22,023 --> 00:08:23,483 Differential diagnosis. Go. 140 00:08:23,608 --> 00:08:25,443 Could be epilepsy or seizure disorder. 141 00:08:25,568 --> 00:08:28,988 Not with the tachycardia. It could be a virus in his brain. 142 00:08:29,114 --> 00:08:31,199 Your specificity's impressive. 143 00:08:31,324 --> 00:08:32,951 Ad renoleukodystrophy. 144 00:08:33,076 --> 00:08:34,160 Could be MS. 145 00:08:34,285 --> 00:08:37,080 The seizures could be caused by plaques and lesions on the brain. 146 00:08:37,205 --> 00:08:39,707 Well, let's find out which. Get him an MRI. 147 00:08:39,833 --> 00:08:41,501 No nuclear imaging! 148 00:08:43,211 --> 00:08:47,590 He wouldn't survive the move to Radiology. MRI and CT scan are both out. 149 00:08:47,715 --> 00:08:50,969 Okay, lumbar puncture will tell us if his proteins are elevated, 150 00:08:51,094 --> 00:08:52,220 at least we can exclude MS. 151 00:08:52,387 --> 00:08:54,347 We can't do a lumbar puncture either. 152 00:08:56,182 --> 00:08:58,268 You're cramping my exits. 153 00:08:58,393 --> 00:09:00,145 Don't tell me, no skin on his spine. 154 00:09:00,270 --> 00:09:03,231 We'd be inserting a needle into an area that's teeming with bacteria. 155 00:09:03,356 --> 00:09:06,109 If he doesn't have a brain infection already, we'd give him one for sure. 156 00:09:06,234 --> 00:09:08,862 There's no other way to look at a brain. 157 00:09:09,696 --> 00:09:12,031 Transcranial Doppler Sonography. 158 00:09:12,157 --> 00:09:15,326 She said "brain", not "pregnant woman's uterus." 159 00:09:15,451 --> 00:09:18,121 They do sound alike. I used one to look at a brain this morning. 160 00:09:18,246 --> 00:09:20,790 Why didn't you take the patient to Radiology, get an MRA? 161 00:09:20,915 --> 00:09:23,001 Obviously I was doing something illegal. 162 00:09:23,126 --> 00:09:25,420 Using nuclear imaging would have raised questions. 163 00:09:25,545 --> 00:09:28,256 You're not gonna get a diagnosis of MS from a sonogram. 164 00:09:28,381 --> 00:09:30,425 Not definitively, but patients with MS 165 00:09:30,550 --> 00:09:33,386 have more reactive neurons in their occipital cortex. 166 00:09:37,390 --> 00:09:38,558 Okay then. 167 00:09:41,686 --> 00:09:44,606 Thank you for all coming to today's lecture 168 00:09:44,731 --> 00:09:46,774 by Dr. Phillip Weber, 169 00:09:47,317 --> 00:09:49,861 who is our guest today at our hospital 170 00:09:49,986 --> 00:09:53,364 to talk about headaches. 171 00:09:54,532 --> 00:09:58,453 Dr. Weber is at the Weber Center for Pain, that makes sense. 172 00:09:58,703 --> 00:10:01,456 Weber, Weber. So please welcome Dr. Weber! 173 00:10:09,005 --> 00:10:12,091 Thank you Dr. Cuddy. 174 00:10:12,300 --> 00:10:14,177 (AUDIENCE LAUGHING) 175 00:10:14,385 --> 00:10:18,014 I suppose I should tell you a little bit more about myself. 176 00:10:18,723 --> 00:10:21,100 I went to school in Virginia. 177 00:10:22,101 --> 00:10:24,103 You've never been to one of these things in your life. 178 00:10:24,229 --> 00:10:26,606 - Who is this guy? - No idea. 179 00:10:28,024 --> 00:10:29,901 What's with the outfit? 180 00:10:30,443 --> 00:10:33,196 Sudden chills and light sensitivity. 181 00:10:33,446 --> 00:10:35,031 Inexplicable. 182 00:10:35,823 --> 00:10:39,327 I received my medical degree at Johns Hopkins University, 183 00:10:39,869 --> 00:10:42,789 where I studied under Brightman and Gilmar... 184 00:10:42,914 --> 00:10:44,666 Hmm. He must be good. 185 00:10:44,791 --> 00:10:47,794 You went to Hopkins, and studied under Brightman and Gilmar. 186 00:10:47,919 --> 00:10:49,379 Shh. 187 00:10:49,504 --> 00:10:52,715 ...helped me win the Doyle Internship at the Mayo Clinic. 188 00:10:52,840 --> 00:10:55,802 You were supposed to get the Doyle Internship. 189 00:10:58,346 --> 00:11:01,933 This guy's Von Lieberlnan? The guy who got you thrown out for cheating? 190 00:11:02,058 --> 00:11:05,687 The dean threw me out. Von Lieberman just ratted on me. 191 00:11:05,812 --> 00:11:08,064 This guy's name is Weber, not Von Lieberman. 192 00:11:08,189 --> 00:11:11,401 I call Weber Von Lieberman, way eviler. 193 00:11:11,818 --> 00:11:12,819 Shh. 194 00:11:13,861 --> 00:11:17,991 ...1D receptors have improved the acute treatment of migraines, 195 00:11:18,825 --> 00:11:20,535 to this point... 196 00:11:20,660 --> 00:11:22,078 So what's the plan? 197 00:11:22,203 --> 00:11:25,623 You gonna wait until he bends over and make a fart sound? 198 00:11:25,915 --> 00:11:29,794 I'm not here about the past. He's a bad scientist. 199 00:11:30,920 --> 00:11:33,840 Well, you cheated off him, how bad can he be? 200 00:11:35,425 --> 00:11:37,385 He got the answer wrong. 201 00:11:45,101 --> 00:11:46,686 DOUG: Are they trying to wake him up? 202 00:11:46,811 --> 00:11:49,063 They can't do that, right? He'll be in too much pain. 203 00:11:49,188 --> 00:11:51,524 Don't worry, he's still under. 204 00:11:51,649 --> 00:11:54,694 But the brain never completely sleeps, it's always working. 205 00:11:54,819 --> 00:11:58,406 Controlling your heart rate, breathing, temperature. 206 00:11:59,365 --> 00:12:01,492 The eyes respond to visual stimuli. 207 00:12:01,617 --> 00:12:03,536 Blood flow increases in certain areas of the brain 208 00:12:03,661 --> 00:12:06,247 and we can track that with a sonogram. 209 00:12:06,372 --> 00:12:10,668 With MS, blood vessels are more reactive, so flow is faster. 210 00:12:10,918 --> 00:12:13,004 If Adam has an infection, 211 00:12:13,212 --> 00:12:15,506 there'd be swelling, which would constrict the arteries. 212 00:12:15,631 --> 00:12:17,884 And the flow would be slower. 213 00:12:18,009 --> 00:12:20,762 Chase. Near the subarachnoid space. 214 00:12:27,143 --> 00:12:31,189 WEBER: Data from control subjects were analyzed of a two-way ANOVA 215 00:12:31,314 --> 00:12:34,400 with status and side as within-subject factors. 216 00:12:35,777 --> 00:12:39,405 You stalked this guy for 20 years just for this shot to humiliate him? 217 00:12:39,530 --> 00:12:41,449 I'm trying to learn. 218 00:12:41,574 --> 00:12:43,951 ...vessels without significant rebound... 219 00:12:44,077 --> 00:12:46,621 He doesn't even know what that means. 220 00:12:46,746 --> 00:12:48,289 You're gonna interrupt him, aren't you? 221 00:12:48,414 --> 00:12:49,916 If I have a question. 222 00:12:50,041 --> 00:12:51,959 And what's that gonna accomplish? 223 00:12:52,085 --> 00:12:55,755 Why can't you just enjoy this? Why can't you just be happy for me? 224 00:12:55,880 --> 00:13:00,259 You have got to find less debilitating outlets than humiliating people. 225 00:13:00,385 --> 00:13:03,721 I hear bowling is more fun than stalking. 226 00:13:04,472 --> 00:13:05,848 But I'm better at this. 227 00:13:05,973 --> 00:13:08,518 ...if "P" is less than point-zero... 228 00:13:08,643 --> 00:13:10,978 Blow a ton of money on a plasma TV. 229 00:13:12,480 --> 00:13:14,524 We found a subarachnoid bleed. 230 00:13:15,942 --> 00:13:18,528 Bleed in the head isn't causing seizures. 231 00:13:18,653 --> 00:13:21,739 It could be. 10% with damage to cerebral cortex have a seizure. 232 00:13:21,864 --> 00:13:23,533 Or bacterial meningitis. 233 00:13:23,658 --> 00:13:25,660 - Viral encephalitis? - There's no way to tell without... 234 00:13:25,785 --> 00:13:27,036 Shut up! 235 00:13:28,287 --> 00:13:29,539 Excuse me. 236 00:13:30,873 --> 00:13:32,208 Not you. 237 00:13:32,333 --> 00:13:35,878 You know, if my lecture is interrupting your meeting, I can wait. 238 00:13:36,003 --> 00:13:37,463 (SPEAKING HINDI) 239 00:13:38,881 --> 00:13:41,884 As your people say in India. Appreciate it. 240 00:13:42,009 --> 00:13:45,680 We'll figure out why later. Fix the bleed or he dies. 241 00:13:45,805 --> 00:13:47,807 Talk to you in a couple hours. 242 00:13:50,351 --> 00:13:51,352 (SPEAKING HINDI) 243 00:14:01,779 --> 00:14:04,073 I'm in the subarachnoid space. 244 00:14:05,199 --> 00:14:07,285 - Can you get it? - Think so. 245 00:14:09,745 --> 00:14:11,747 Put the probe back where it was so I can see the wire! 246 00:14:11,873 --> 00:14:12,957 We're looking for the bleed in... 247 00:14:13,082 --> 00:14:17,211 Look when I get there, I'm flying blind without a contrast CT here! 248 00:14:26,262 --> 00:14:30,725 ...and with a p-value of less than 0.001, 249 00:14:31,142 --> 00:14:35,354 we have strong statistical evidence that this drug prevents migraine headaches 250 00:14:35,480 --> 00:14:37,899 without daily administration. 251 00:14:38,441 --> 00:14:40,151 Excuse me, Doctor. 252 00:14:40,276 --> 00:14:41,819 He knows his field better than you do. 253 00:14:41,944 --> 00:14:45,865 It's always been my understanding that, unless you follow a daily regimen, 254 00:14:45,990 --> 00:14:47,992 no drug can prevent a migraine. 255 00:14:48,117 --> 00:14:49,952 That's why they call it a breakthrough. 256 00:14:50,077 --> 00:14:52,288 That's why you call it a breakthrough. 257 00:14:52,413 --> 00:14:55,500 No, the pharmaceutical company sponsoring my clinical trials 258 00:14:55,625 --> 00:14:57,877 also hails it as a breakthrough. 259 00:14:58,002 --> 00:15:00,505 I'm sure your wife and lawyer do, too. 260 00:15:01,881 --> 00:15:04,258 Is there anybody who doesn't stand to make a fortune from it 261 00:15:04,383 --> 00:15:05,676 calling it a breakthrough? 262 00:15:05,801 --> 00:15:06,969 Who are you? 263 00:15:07,094 --> 00:15:09,430 Just a lunatic who desperately needs a hobby. 264 00:15:09,555 --> 00:15:11,516 How exactly do these studies work? 265 00:15:11,641 --> 00:15:13,518 Do you give this drug to a bunch of people, 266 00:15:13,643 --> 00:15:17,396 and if they don't get a migraine, you go, "Voilà, my drug works"? 267 00:15:17,522 --> 00:15:18,981 Excuse me, miss? 268 00:15:19,440 --> 00:15:21,150 Do you have cancer? 269 00:15:22,610 --> 00:15:25,571 Wow! Mango juice prevents cancer. 270 00:15:26,155 --> 00:15:29,408 Perhaps I should have taken my medication before this lecture. 271 00:15:31,369 --> 00:15:35,790 WEBER: We had a very specific control group, chronic migraine sufferers. 272 00:15:35,915 --> 00:15:38,042 I don't have time to go through all the math right now, 273 00:15:38,167 --> 00:15:41,462 - but the incidence was dramatically... - Sure, in India. 274 00:15:42,213 --> 00:15:44,799 Two plus two equals five there, right? 275 00:15:45,800 --> 00:15:47,134 Do I know you? 276 00:15:47,260 --> 00:15:50,721 I know your math skills. They blow. 277 00:15:51,430 --> 00:15:52,431 Touché. 278 00:15:52,557 --> 00:15:54,392 You sound very familiar. 279 00:15:54,517 --> 00:15:57,311 Why did you publish it in an obscure journal in India? 280 00:15:57,436 --> 00:16:02,108 Why not publish it in really, really cool head cases of South Philly? 281 00:16:02,233 --> 00:16:04,819 Neuroscience New Delhi is a respected journal. 282 00:16:04,944 --> 00:16:08,489 Yeah. The guy running Slurp N' Gulp tells me it's one of the best. 283 00:16:08,614 --> 00:16:10,491 Get a hooker, anything. 284 00:16:10,616 --> 00:16:14,328 See, I'm thinking that publishing studies is probably the easiest way 285 00:16:14,453 --> 00:16:16,956 to get a pharlnaceutical company to give you a reach-around. 286 00:16:17,081 --> 00:16:20,167 And choosing a journal that no one can actually read, well, that's... 287 00:16:20,293 --> 00:16:21,502 That's shrewd. 288 00:16:21,627 --> 00:16:25,298 - I know I know you. - Sure you do, Dick. 289 00:16:25,631 --> 00:16:26,716 The name's Philip. 290 00:16:26,841 --> 00:16:29,927 My bad. Something to do with your face. 291 00:16:30,052 --> 00:16:32,305 I always think your name is Dick. 292 00:16:32,430 --> 00:16:34,390 - House? - Here. 293 00:16:36,309 --> 00:16:40,104 Medical school was 20 years ago. Give it a rest. Grow up. 294 00:16:40,229 --> 00:16:44,900 Yeah. You were always the grown-up. Do the responsible thing, tattletale! 295 00:16:45,484 --> 00:16:48,487 - You cheated! - I cheated then, you're cheating now! 296 00:16:48,613 --> 00:16:49,447 Your drug doesn't work. 297 00:16:49,572 --> 00:16:53,117 Oh, yes, you would like to believe that because it plays right into your fantasy... 298 00:16:53,242 --> 00:16:55,202 - I tested it. - Oh, really? 299 00:16:55,369 --> 00:16:58,539 What are your parameters? Where's your study? 300 00:17:00,916 --> 00:17:02,501 Room 2134. 301 00:17:02,877 --> 00:17:05,254 - One patient? - The coma patient? 302 00:17:06,589 --> 00:17:08,382 You haven't changed a bit. 303 00:17:09,342 --> 00:17:13,179 You took shortcuts in med school, you're taking shortcuts now. 304 00:17:13,429 --> 00:17:16,515 You cannot test this on an abnormal brain. 305 00:17:16,641 --> 00:17:20,645 That's so close-minded. He's not abnorlnal, he's special. 306 00:17:20,770 --> 00:17:24,273 Cerebral cortex atrophies in coma patients. 307 00:17:26,150 --> 00:17:28,736 You need live, conscious people. 308 00:17:32,573 --> 00:17:34,867 You don't know everything, House! 309 00:17:38,913 --> 00:17:41,582 FOREMAN: Something that disrupts brain function. 310 00:17:41,916 --> 00:17:45,461 Plaques are perfect. Interrupt neuronal communication. 311 00:17:45,586 --> 00:17:47,713 - MS? - No, MS is complicated. 312 00:17:47,838 --> 00:17:51,592 I think this is more basic. It's just tachycardia and seizures. 313 00:17:51,717 --> 00:17:54,762 How much longer the Burn Unit guys gonna keep him in that thing? 314 00:17:54,887 --> 00:17:57,723 Lecture's over, let's go. House wants to... 315 00:18:00,601 --> 00:18:02,520 Adam's waking up. 316 00:18:02,770 --> 00:18:04,522 Get the anesthesiologist in here now. 317 00:18:04,647 --> 00:18:05,981 CAMERON: He's in pain. 318 00:18:07,483 --> 00:18:09,568 That's not pain. 319 00:18:10,236 --> 00:18:12,154 Need some help in here! 320 00:19:14,091 --> 00:19:15,801 Adam had an orgasm. 321 00:19:17,553 --> 00:19:20,556 What? You mean, while he was sedated... 322 00:19:22,600 --> 00:19:23,601 (HOUSE EXCLAIMING) 323 00:19:26,979 --> 00:19:28,564 What's wrong? 324 00:19:30,024 --> 00:19:31,984 I'm having a migraine. 325 00:19:32,485 --> 00:19:33,819 Are you okay? 326 00:19:35,196 --> 00:19:36,322 Yes. 327 00:19:38,032 --> 00:19:39,325 I was right. 328 00:19:41,494 --> 00:19:42,495 (GROANING) 329 00:19:51,504 --> 00:19:53,422 I'm gonna knock you out for a couple of hours. 330 00:19:53,547 --> 00:19:55,508 No, I got work to do. 331 00:19:55,716 --> 00:19:58,511 Just give me sumatriptan for the pain 332 00:19:58,636 --> 00:20:01,222 and verapamil so it doesn't recur. 333 00:20:04,809 --> 00:20:08,562 I heard the patient had fun in the hyperbaric chamber. 334 00:20:08,687 --> 00:20:09,563 Yeah. 335 00:20:09,688 --> 00:20:12,399 Gotta schedule me some time in there. 336 00:20:14,985 --> 00:20:17,780 Weber's meds aren't even legal in the U.S. 337 00:20:18,072 --> 00:20:19,782 It's legal in India. 338 00:20:21,325 --> 00:20:22,952 I was disoriented. 339 00:20:28,833 --> 00:20:31,043 Moving around is a bad idea. 340 00:20:31,502 --> 00:20:34,088 Hey, if you feel chest pain, you need to let me know. 341 00:20:34,213 --> 00:20:37,091 Verapamil can cause congestive heart failure. 342 00:20:37,258 --> 00:20:39,301 Nothing can hurt my heart. 343 00:20:42,429 --> 00:20:46,600 Hey, you're gonna feel some dizziness. Definitely gonna be constipated. 344 00:20:51,313 --> 00:20:55,109 Differential diagnosis for getting off. 345 00:20:55,860 --> 00:20:56,694 Is he gonna be okay? 346 00:20:56,819 --> 00:20:59,321 No. Something's seriously wrong with him. 347 00:20:59,446 --> 00:21:03,951 Differential diagnosis for ejaculation. 348 00:21:06,412 --> 00:21:07,955 Don't make me say it again. 349 00:21:08,080 --> 00:21:10,249 We're not stalling, we just don't know. 350 00:21:10,374 --> 00:21:11,542 Then guess. 351 00:21:12,209 --> 00:21:14,962 - Could pain medication cause an orgasm? - I wish. 352 00:21:15,087 --> 00:21:17,006 Maybe pain caused the orgasm. 353 00:21:17,131 --> 00:21:20,384 You get a tattoo, the brain releases endorphins which create pleasure. 354 00:21:20,509 --> 00:21:23,178 Most people don't orgasm from a needle prick. 355 00:21:23,304 --> 00:21:25,097 HOUSE: Well, Chase has a point. 356 00:21:25,222 --> 00:21:28,809 The brain is like a huge train station, if the switches... 357 00:21:29,685 --> 00:21:30,686 (GROANING) 358 00:21:32,187 --> 00:21:34,148 You're the neurologist, talk for me. 359 00:21:34,273 --> 00:21:38,360 If sensory inforlnation got misinterpreted by the medial forebrain bundle, 360 00:21:38,485 --> 00:21:41,363 it's possible for bad to feel good, and good to feel bad. 361 00:21:41,488 --> 00:21:45,034 He's a lucky kid. Let's not fix him until the burns heal. 362 00:21:45,159 --> 00:21:47,202 So what attacks the medial forebrain bundle? 363 00:21:47,328 --> 00:21:49,371 Infective neuropathies, vasculitic neuropathies... 364 00:21:49,496 --> 00:21:51,624 Krabbe's disease, metachromatic leukodystrophy. 365 00:21:51,749 --> 00:21:54,376 HOUSE: All very bad things. 366 00:21:54,501 --> 00:21:57,254 No way to look for any of them in his condition. 367 00:21:57,379 --> 00:21:58,547 Could be an infection. 368 00:21:58,672 --> 00:22:00,215 I said infection about eight seconds ago. 369 00:22:00,341 --> 00:22:02,343 You listed some brain infections. 370 00:22:02,468 --> 00:22:07,056 But what if it's just a regular old infection festering in the burned skin? 371 00:22:07,181 --> 00:22:09,558 Pus on his arm isn't causing problems in the forebrain. 372 00:22:09,683 --> 00:22:13,354 He's on 20 different medications to manage his pain, his heart, 373 00:22:13,479 --> 00:22:15,022 how often he urinates. 374 00:22:15,147 --> 00:22:17,650 His brain is like a waiter that's got too many... 375 00:22:17,775 --> 00:22:20,402 Hey, hey. I do the metaphors. 376 00:22:22,446 --> 00:22:24,198 The brain is stressed. 377 00:22:24,323 --> 00:22:26,283 An infection elsewhere could put it over the edge. 378 00:22:26,408 --> 00:22:29,495 So we just wait for his burns to heal to see if you're right? 379 00:22:29,620 --> 00:22:32,915 If you're wrong, he doesn't have that kind of time. 380 00:22:34,208 --> 00:22:35,918 Dominic Larrey. 381 00:22:36,752 --> 00:22:38,796 He another dead doctor? 382 00:22:38,921 --> 00:22:41,465 He's Napoleon's Surgeon in Chief. 383 00:22:41,590 --> 00:22:43,258 Cleaned a lot of battle wounds. 384 00:22:43,384 --> 00:22:44,593 By amputating legs. 385 00:22:44,718 --> 00:22:46,261 And with bugs. 386 00:22:51,225 --> 00:22:54,228 CAMERON: Maggots are implanted directly into Adam's burns. 387 00:22:55,270 --> 00:22:58,273 Maggots, they eat dead people, I... 388 00:22:58,399 --> 00:23:01,694 Maggots eat dead flesh. Only dead flesh. 389 00:23:02,361 --> 00:23:05,364 So they're perfectly suited to clean wounds. 390 00:23:06,198 --> 00:23:09,410 They also kill the bacteria that thrive in injured tissues. 391 00:23:39,481 --> 00:23:40,649 (EXCLAIMING) 392 00:23:47,364 --> 00:23:48,490 Dr. Jekyll, I presume. 393 00:23:48,615 --> 00:23:52,411 They found a half-eaten sheep in the zoo. The police wanna ask you a few questions. 394 00:23:52,536 --> 00:23:53,996 I need something to wash it down. 395 00:23:54,121 --> 00:23:56,165 Coffee? Bad idea. 396 00:23:56,290 --> 00:23:59,376 - You're better off with water! - Coffee's closer. 397 00:24:01,336 --> 00:24:03,297 Foolproof plan, by the way. 398 00:24:03,422 --> 00:24:05,132 Either his meds would work, 399 00:24:05,257 --> 00:24:09,762 and you'd be in psychic pain because Von Evil is gonna be rich. 400 00:24:10,804 --> 00:24:14,433 Or they wouldn't, and you get to be in agony all day. 401 00:24:15,601 --> 00:24:18,562 Perfect lose-lose situation. Very you. 402 00:24:18,687 --> 00:24:21,440 - I had to prove... - You've proved nothing. 403 00:24:24,068 --> 00:24:26,904 Right. This isn't a migraine. 404 00:24:27,654 --> 00:24:29,823 Yeah. "Dear New England Journal of Medicine, 405 00:24:29,948 --> 00:24:32,534 I took this guy's drug and still got a headache. 406 00:24:32,659 --> 00:24:36,455 Thus, scientifically proving that my arch enemy is an idiot." 407 00:24:36,580 --> 00:24:37,706 You just wanted the pain. 408 00:24:37,831 --> 00:24:41,418 Meds are supposed to prevent migraine. 409 00:24:41,543 --> 00:24:43,045 You get distracted by pain. 410 00:24:43,170 --> 00:24:45,839 Leaves less room for the things you don't wanna think about. 411 00:24:45,964 --> 00:24:49,301 Like the Flyers sucking, or the price of gas, 412 00:24:49,468 --> 00:24:52,721 or the fact that you pushed the love of your life out of your life. 413 00:24:52,846 --> 00:24:55,557 God, I wish the pain would go away. 414 00:24:55,974 --> 00:24:58,769 Next time you need to get your mind off her, stick a needle in your eye. 415 00:24:58,894 --> 00:25:02,689 It's less annoying to the rest of us when you can still walk. 416 00:25:09,905 --> 00:25:11,573 CAMERON: Did you sleep here? 417 00:25:15,494 --> 00:25:16,453 Lower. 418 00:25:17,371 --> 00:25:19,081 Do you want a pillow? 419 00:25:20,082 --> 00:25:21,667 Not softer, lower. 420 00:25:22,417 --> 00:25:24,920 Frequency of your voice is grating. 421 00:25:25,045 --> 00:25:26,672 You should've been better by now. 422 00:25:26,797 --> 00:25:28,423 I'm super. 423 00:25:28,674 --> 00:25:30,050 Patient? 424 00:25:30,467 --> 00:25:33,095 The maggots did great for the burn. 425 00:25:33,512 --> 00:25:35,389 But the brain waves are still all over the map. 426 00:25:35,514 --> 00:25:39,768 Which means your regular old infection isn't causing his brain dysfunction. 427 00:25:39,893 --> 00:25:41,687 Which means there's an underlying condition, 428 00:25:41,812 --> 00:25:44,439 which means we've gotta get inside his head. 429 00:25:44,565 --> 00:25:46,525 Do a lumbar puncture. 430 00:25:46,650 --> 00:25:48,652 We've already established that we can't get a lumbar... 431 00:25:48,777 --> 00:25:50,737 C2, C3. 432 00:25:50,863 --> 00:25:52,823 No. No. No way. 433 00:25:53,574 --> 00:25:56,910 I only saw a cervical tap once, and that guy got paralyzed. 434 00:25:57,035 --> 00:26:01,540 Ask the parents if they prefer to have their son in a wheelchair or dead. 435 00:26:05,961 --> 00:26:08,839 Something's causing his brain to lose control. 436 00:26:08,964 --> 00:26:10,799 Eventually it'll shut off. 437 00:26:10,924 --> 00:26:12,551 We need to do a lumbar puncture 438 00:26:12,676 --> 00:26:15,304 to get some of the fluid in his spine so we can test it. 439 00:26:15,429 --> 00:26:17,347 You need us to sign a consent? 440 00:26:17,472 --> 00:26:19,349 I have to warn you. 441 00:26:19,474 --> 00:26:22,436 There's a serious risk of paralysis or death. 442 00:26:23,353 --> 00:26:25,105 Are you saying we shouldn't do this? 443 00:26:25,689 --> 00:26:26,982 You have to do this. 444 00:26:27,107 --> 00:26:28,901 Then why are you telling us what can go wrong? 445 00:26:29,026 --> 00:26:31,111 - I just think you should know... - Either you're cruel 446 00:26:31,236 --> 00:26:33,071 or this clipboard is a way for you to cover your ass, 447 00:26:33,197 --> 00:26:34,865 - in case you cripple our son. - This isn't his fault. 448 00:26:34,990 --> 00:26:38,035 No, it's not. It's yours, that's what you keep telling me. 449 00:26:38,160 --> 00:26:39,661 My son is lying in there half-dead, 450 00:26:39,786 --> 00:26:43,040 I am just trying to find a way to get through this. 451 00:26:43,165 --> 00:26:45,292 - I'm sorry. - Yeah, I know. 452 00:26:48,962 --> 00:26:50,214 (MONITOR BEEPING) 453 00:27:05,354 --> 00:27:06,355 Needle. 454 00:27:21,787 --> 00:27:24,414 - It's not going in. - Don't force it. 455 00:27:24,706 --> 00:27:25,999 I'm going one space higher. 456 00:27:26,124 --> 00:27:29,336 It's too close to his brain stem, it'll herniate. 457 00:27:29,461 --> 00:27:32,547 - You're gonna paralyze him. - You're not helping. 458 00:27:32,756 --> 00:27:34,299 His blood pressure's spiking, stop. 459 00:27:34,424 --> 00:27:35,467 I can get it. 460 00:27:35,592 --> 00:27:38,095 (MONITOR BEEPING RAPIDLY) He's 180 over 120, he's gonna stroke. 461 00:27:39,680 --> 00:27:42,307 I'm in the space. Give me the vial. 462 00:27:52,067 --> 00:27:53,902 (MONITOR BEEPING RHYTHMICALLY) 463 00:27:59,700 --> 00:28:02,327 He doesn't have MS or an infection. 464 00:28:04,288 --> 00:28:06,498 His proteins aren't elevated? 465 00:28:06,623 --> 00:28:09,418 Wrong protein. lgM, not lgG. 466 00:28:09,543 --> 00:28:12,379 Elevation was probably caused by the bleed. 467 00:28:13,755 --> 00:28:17,801 What if there was tingling in his extremities prior to the crash? 468 00:28:18,593 --> 00:28:21,930 - How can you still be on MS? - I gotta be on something. 469 00:28:22,514 --> 00:28:26,560 Something's interrupting his neurons' chitchat, like lesions. 470 00:28:26,685 --> 00:28:28,353 We can't scan for them. 471 00:28:28,478 --> 00:28:31,398 The only test we can do, we just did and it was negative. 472 00:28:31,523 --> 00:28:33,567 He has no tingling, no numbness. 473 00:28:33,692 --> 00:28:36,236 And you read his history, parents didn't say anything about... 474 00:28:36,361 --> 00:28:37,821 What about Adam? 475 00:28:39,281 --> 00:28:43,160 We can't look into his brain, but you want us to read his mind? 476 00:28:44,077 --> 00:28:45,579 Good point. 477 00:28:50,709 --> 00:28:51,793 (DOOR OPENING) 478 00:28:54,796 --> 00:28:57,507 Yeah, you can finish the sponge bath in a minute. 479 00:28:57,632 --> 00:29:00,802 They're just re-doing his dressings. He's out, he's fine. 480 00:29:00,927 --> 00:29:04,765 I didn't page you to put him out. I paged you to wake him up. 481 00:29:04,931 --> 00:29:07,392 Why are these lights so damn bright? 482 00:29:07,976 --> 00:29:09,436 Thank you. 483 00:29:09,561 --> 00:29:11,521 Come on, I need to talk to him. 484 00:29:11,646 --> 00:29:14,232 House, you can't wake up a burn victim to play twenty questions. 485 00:29:14,358 --> 00:29:16,276 - It's torture. - He won't remember. 486 00:29:16,401 --> 00:29:18,945 - He's gonna be in extraordinary... - God, you're good! 487 00:29:19,071 --> 00:29:20,781 You're putting me to sleep. 488 00:29:20,906 --> 00:29:24,326 I know he's gonna be in pain, I know you disapprove. I'm his attending. 489 00:29:24,451 --> 00:29:25,911 Wake him up. 490 00:29:43,220 --> 00:29:45,430 (GASPING) 491 00:29:45,555 --> 00:29:46,890 Oh, my God! 492 00:29:47,015 --> 00:29:49,393 - I'm Dr. House. - It hurts! 493 00:29:49,559 --> 00:29:51,520 It's gonna get a lot worse, so answer fast. 494 00:29:51,645 --> 00:29:56,483 Before the accident, did you experience any numbness or tingling in your fingers? 495 00:29:56,608 --> 00:29:58,944 You got burned, it's healing, I need an answer. 496 00:29:59,069 --> 00:30:00,278 It really hurts! 497 00:30:00,404 --> 00:30:02,239 Any tingling in your arms or legs? 498 00:30:02,364 --> 00:30:03,949 You gotta do something, I can't... 499 00:30:04,074 --> 00:30:07,452 Adam, you gotta listen to me, did you feel anything? 500 00:30:07,577 --> 00:30:08,870 (CRYING IN PAIN) 501 00:30:08,995 --> 00:30:13,458 I pissed in my pants and then I don't remember... 502 00:30:15,961 --> 00:30:18,380 (SCREAMING IN PAIN) 503 00:30:52,831 --> 00:30:55,542 - Was he okay? - Get everyone in my office. 504 00:30:56,668 --> 00:30:58,462 Where you going? 505 00:30:58,670 --> 00:31:02,632 Kid's screaming gave me a headache. I gotta take an aspirin. 506 00:32:01,566 --> 00:32:04,861 House, you okay? We've been waiting for you. 507 00:32:09,491 --> 00:32:11,326 I'm hallucinating. 508 00:32:14,538 --> 00:32:17,791 Hallucinations with migraines are pretty uncommon. 509 00:32:18,500 --> 00:32:21,836 - What did you see? - I saw music. 510 00:32:23,755 --> 00:32:26,299 Sensory deception makes no sense. 511 00:32:30,679 --> 00:32:32,389 You took something. 512 00:32:33,056 --> 00:32:35,517 The kid's fighting for his life. 513 00:33:05,505 --> 00:33:06,840 Hey, you find him? 514 00:33:06,965 --> 00:33:09,050 He was hallucinating in the locker room. 515 00:33:09,175 --> 00:33:10,385 He okay? 516 00:33:10,510 --> 00:33:12,220 He's feeling no pain, he's high. 517 00:33:12,345 --> 00:33:13,680 Vicodin high? 518 00:33:13,805 --> 00:33:16,266 Past that. He's seeing sounds. 519 00:33:16,600 --> 00:33:18,310 Took something. 520 00:33:21,146 --> 00:33:23,732 Why is it so dark in here? It's a beautiful day outside. 521 00:33:23,857 --> 00:33:26,359 Open the shades, let the sun shine in. 522 00:33:26,484 --> 00:33:28,153 It's nighttime. 523 00:33:29,946 --> 00:33:32,907 - It's still Tuesday, right? - You look better. 524 00:33:33,366 --> 00:33:35,910 - I took something. - Mind if I ask what? 525 00:33:37,412 --> 00:33:39,497 Little of this, little of that. 526 00:33:39,623 --> 00:33:41,583 I know what's wrong with our patient. 527 00:33:41,708 --> 00:33:43,335 He's depressed. 528 00:33:43,460 --> 00:33:45,045 - He told you that when you woke him up? - Nope. 529 00:33:45,170 --> 00:33:46,838 He told me he pissed his pants and blacked out. 530 00:33:46,963 --> 00:33:50,175 That's not diagnostic of depression. Lack of appetite, isolating yourself. 531 00:33:50,300 --> 00:33:53,428 Uncontrollable urination and blacking out are good predictors of what? 532 00:33:53,553 --> 00:33:54,387 Seizure. 533 00:33:54,512 --> 00:33:56,973 Which means the seizure he had when you tested his heart 534 00:33:57,098 --> 00:33:59,017 - was at least his second seizure. - So what? 535 00:33:59,142 --> 00:34:00,685 Depression and seizures aren't correlated. 536 00:34:00,810 --> 00:34:03,438 No, but you know what is? 537 00:34:03,563 --> 00:34:06,274 Depression and anti-depression medicine. 538 00:34:06,399 --> 00:34:07,817 Tox screen was clean. 539 00:34:07,942 --> 00:34:10,153 Yeah, but you know how much crap he's got in his system 540 00:34:10,278 --> 00:34:11,446 for dealing with those burns. 541 00:34:11,571 --> 00:34:14,240 The guy could have the Spanish Arlnada floating through his bloodstream 542 00:34:14,366 --> 00:34:17,077 and we wouldn't know about it, till they started firing cannons. 543 00:34:17,202 --> 00:34:20,664 Antidepressants have been known to cause seizures in kids, but not orgasms. 544 00:34:20,789 --> 00:34:21,790 This is a brain in trouble. 545 00:34:21,915 --> 00:34:24,959 This is a brain with too much serotonin. 546 00:34:25,085 --> 00:34:28,797 Serotonin affects mood, appetite, it doesn't cause the brain to shut down. 547 00:34:28,922 --> 00:34:32,050 Antidepressants fake brains into thinking they have more serotonin 548 00:34:32,175 --> 00:34:33,301 than they actually do. 549 00:34:33,426 --> 00:34:37,305 Every ten million or so cases sets off a chain reaction. 550 00:34:37,430 --> 00:34:39,933 Produces too much, enough to fry itself. 551 00:34:40,058 --> 00:34:42,477 If Adam has Serotonin Storm, it's deadly. 552 00:34:42,602 --> 00:34:44,604 But treatable. Cyproheptadine. 553 00:34:44,729 --> 00:34:46,398 Unless he doesn't have Serotonin Storm. 554 00:34:46,523 --> 00:34:49,025 He could just as easily have too much dopamine as serotonin, 555 00:34:49,150 --> 00:34:52,570 but if it's dopamine, the cyproheptadine will kill him. 556 00:34:52,696 --> 00:34:53,530 Where are you going? 557 00:34:53,655 --> 00:34:55,615 Gonna talk to the kid again, he seems nice. 558 00:34:55,740 --> 00:34:57,158 You can't. 559 00:34:57,409 --> 00:34:59,035 Why? Did he say he doesn't like me? 560 00:34:59,160 --> 00:35:02,288 Anesthesiologist told the parents what you did. 561 00:35:02,414 --> 00:35:04,457 Everyone's a tattletale. 562 00:35:10,755 --> 00:35:12,590 Is your son depressed? 563 00:35:14,300 --> 00:35:16,636 - No. Who are you? - I'm Dr. House. 564 00:35:16,761 --> 00:35:18,054 Oh, you're the idiot who thought... 565 00:35:18,179 --> 00:35:19,889 I heard him screaming all the way down the hallway. 566 00:35:20,014 --> 00:35:22,809 If I didn't wake him up, I wouldn't have learned what caused the crash. 567 00:35:22,934 --> 00:35:24,436 He had a seizure. 568 00:35:27,897 --> 00:35:29,691 This wasn't my fault? 569 00:35:30,608 --> 00:35:33,820 Well, if he hadn't had the brain problem, he wouldn't have the burns. 570 00:35:33,945 --> 00:35:36,030 On the other hand, if you hadn't put him on the ATV, 571 00:35:36,156 --> 00:35:37,407 he also wouldn't have the burns. 572 00:35:37,532 --> 00:35:39,451 You can debate your personal responsibility after I leave. 573 00:35:39,576 --> 00:35:41,161 I need to wake him up again. 574 00:35:41,286 --> 00:35:43,037 I need to know if he's taking antidepressants. 575 00:35:43,163 --> 00:35:44,205 He's not. 576 00:35:45,248 --> 00:35:48,918 - He's the happiest kid I know. - But you don't know, do you? 577 00:35:51,129 --> 00:35:52,380 He's my son. 578 00:35:53,089 --> 00:35:54,674 That's sort of my point. 579 00:35:54,799 --> 00:35:58,261 At 16, they'll tell anyone anything, except their parents. 580 00:35:58,386 --> 00:35:59,971 Adam talks to us about everything. 581 00:36:00,096 --> 00:36:02,140 Yeah, I know about the pot and the cocaine. 582 00:36:02,265 --> 00:36:04,142 There was never... Cocaine. What... 583 00:36:04,267 --> 00:36:07,353 Are you sure? Are you having him followed? 584 00:36:07,479 --> 00:36:09,939 He told us when he got drunk at a party. 585 00:36:10,064 --> 00:36:11,816 He told us when he started having sex. 586 00:36:11,941 --> 00:36:13,526 At 16? Way to go. 587 00:36:13,651 --> 00:36:15,278 He told us when he cheated on a math test. 588 00:36:15,403 --> 00:36:17,655 He told us when his girlfriend cheated on him. 589 00:36:17,781 --> 00:36:20,700 - He doesn't hide anything from us. - But if he was depressed? 590 00:36:20,825 --> 00:36:21,868 He'd tell us. 591 00:36:22,327 --> 00:36:25,121 We don't judge, he's not depressed, we're sure. 592 00:36:25,246 --> 00:36:27,373 "Bet his life on it" sure? 593 00:36:29,209 --> 00:36:30,960 Just hypothetically. 594 00:36:32,420 --> 00:36:33,546 Yeah. 595 00:36:37,217 --> 00:36:38,092 Okay- 596 00:36:41,137 --> 00:36:42,430 Kid's happy. 597 00:36:43,348 --> 00:36:45,391 Happy, happy, happy- 598 00:36:45,767 --> 00:36:49,270 Then we're back to where we started. Seizure disorders. 599 00:36:49,395 --> 00:36:52,232 Seizure disorders aren't causing orgasms. 600 00:36:52,357 --> 00:36:53,858 Vascular malformations? 601 00:36:53,983 --> 00:36:56,027 Would've seen it on the sonogram. 602 00:36:56,152 --> 00:36:58,196 Hepatic encephalopathy? 603 00:36:58,321 --> 00:37:00,406 Liver enzyme tests were normal. 604 00:37:06,371 --> 00:37:08,957 - Where are you going? - Take a leak. 605 00:37:17,048 --> 00:37:18,216 What are you doing? 606 00:37:18,341 --> 00:37:20,301 You can't come in here, you're not sterile. 607 00:37:20,426 --> 00:37:21,636 Don't touch our son, we told you... 608 00:37:21,761 --> 00:37:24,222 Seriously, millions of bacteria, microbes on you. 609 00:37:24,347 --> 00:37:27,225 He'll die of sepsis. If you go in there... 610 00:37:31,271 --> 00:37:32,730 I think he's gonna wake him up again. 611 00:37:32,856 --> 00:37:34,274 I know he is. 612 00:37:36,234 --> 00:37:37,986 House, you can't do this. 613 00:37:38,111 --> 00:37:42,240 Oh, if I had a nickel for every time I've heard that. Relax. 614 00:37:42,365 --> 00:37:45,869 Are they gonna sue us? If I'm right, I save his life. 615 00:37:45,994 --> 00:37:48,913 If I'm wrong, he's dead no matter what I do. 616 00:37:49,330 --> 00:37:52,292 Either way, how much have I really hurt them? 617 00:37:52,417 --> 00:37:53,459 Leave him alone! 618 00:37:53,585 --> 00:37:56,045 You're not sterile. Do you wanna kill the kid? 619 00:37:56,170 --> 00:37:58,089 - Give me the syringe. - No pain, no gain. 620 00:37:58,214 --> 00:38:00,174 Hey, you gotta stop this. 621 00:38:04,220 --> 00:38:05,805 They're right. 622 00:38:06,639 --> 00:38:09,309 - He's not depressed. - FOREMAN: Yeah, sure. 623 00:38:09,434 --> 00:38:12,186 I'm not letting you go till you give me that syringe. 624 00:38:12,312 --> 00:38:14,272 What's that on his wrist? 625 00:38:15,356 --> 00:38:16,399 A burn. 626 00:38:16,524 --> 00:38:18,902 - Why on his wrist? - Why not on his wrist? 627 00:38:19,027 --> 00:38:22,864 His back, his torso, everything's a mess. His forearlns are clean. 628 00:38:22,989 --> 00:38:25,199 - Except right there. - So what? 629 00:38:26,492 --> 00:38:27,952 It's a perfect circle. 630 00:38:28,077 --> 00:38:32,165 So a drop of burning gasoline fell on his wrist, a screw from the ATV. 631 00:38:33,082 --> 00:38:34,292 Maybe. 632 00:38:44,385 --> 00:38:47,263 - Why are you torturing him? - Does your son smoke? 633 00:38:48,389 --> 00:38:49,974 I'd kill him. 634 00:38:51,976 --> 00:38:56,189 So, he can talk to you about sex, crack, anything except cigarettes. 635 00:38:57,482 --> 00:39:00,234 He has a cigarette burn on his wrist. 636 00:39:00,735 --> 00:39:04,072 Also a fading nicotine stain between two fingers. 637 00:39:04,822 --> 00:39:08,076 Bad news, your son has a filthy, unhealthy habit. 638 00:39:08,201 --> 00:39:10,370 Good news, he's trying to quit. 639 00:39:10,495 --> 00:39:12,622 Bad news, the quitting's killing him. 640 00:39:12,747 --> 00:39:15,458 Good news, I can cure him. Bad news... 641 00:39:17,043 --> 00:39:21,422 - Nope, that's the end of it. - Quitting smoking can kill? 642 00:39:21,547 --> 00:39:23,549 No-smoke meds are antidepressants. 643 00:39:23,675 --> 00:39:25,718 The crappy ones you get over the Internet 644 00:39:25,843 --> 00:39:28,554 are loaded with whatever antidepressants they can get cheap. 645 00:39:28,680 --> 00:39:33,017 And since Mommy and Daddy obviously didn't take him to a pediatrician... 646 00:39:35,228 --> 00:39:38,439 Sorry, I was wrong about him being depressed. 647 00:39:38,940 --> 00:39:40,358 Treat him. 648 00:39:57,458 --> 00:39:58,292 (DOOR OPENING) 649 00:39:58,418 --> 00:39:59,460 CUDDY: Hey! 650 00:40:00,586 --> 00:40:02,797 Did you drop acid? 651 00:40:04,424 --> 00:40:07,260 - Why would I do that? - To annoy me. 652 00:40:07,427 --> 00:40:09,887 Or maybe because you're miserable, 653 00:40:10,013 --> 00:40:13,349 or because you want to self-destruct. 654 00:40:13,516 --> 00:40:14,892 Pick one. 655 00:40:15,476 --> 00:40:19,439 How about because LSD acts on serotonin receptors in the brain, 656 00:40:19,564 --> 00:40:22,275 which can stop a migraine in its tracks. 657 00:40:22,692 --> 00:40:25,278 I'm just saying that's also a possibility. 658 00:40:25,403 --> 00:40:28,656 - How did you know about it? - Cameron is worried about you. 659 00:40:28,781 --> 00:40:32,618 I told her that LSD lasts up to 12 hours, if you were functional, she must be wrong. 660 00:40:32,744 --> 00:40:35,496 Either that or I also took a whole bunch of antidepressants, 661 00:40:35,621 --> 00:40:37,707 which short-circuited the LSD. 662 00:40:37,832 --> 00:40:39,584 I'm just saying that would also explain it. 663 00:40:39,709 --> 00:40:42,045 Thank you for ruining my clinical trials. 664 00:40:42,170 --> 00:40:44,130 Pharmaceutical company's shutting me down. 665 00:40:44,255 --> 00:40:46,507 - You're kidding. Really? - How could that surprise you? 666 00:40:46,632 --> 00:40:47,592 You sent them an email 667 00:40:47,717 --> 00:40:50,386 complaining about my math, telling them about your stunt. 668 00:40:50,511 --> 00:40:52,472 I didn't know people actually read emails. 669 00:40:52,597 --> 00:40:54,140 Delete button's so conveniently located. 670 00:40:54,265 --> 00:40:57,018 So what's next? You gonna follow me my whole life? 671 00:40:57,143 --> 00:40:58,853 - Torture me? - Why would I do that? 672 00:40:58,978 --> 00:41:03,066 You waited 20 years to do this. What's next? Break up my marriage? 673 00:41:03,941 --> 00:41:07,278 - No. We're even. - Right. 674 00:41:09,405 --> 00:41:11,407 Oh, thanks for setting me up. 675 00:41:15,286 --> 00:41:18,498 Eye for an eye, LSD and antidepressants. 676 00:41:19,499 --> 00:41:21,292 Everything in balance. 677 00:41:21,417 --> 00:41:24,462 Buddhists call it Karma. Christians call it the Golden Rule. 678 00:41:24,587 --> 00:41:26,047 Jews call it... 679 00:41:28,091 --> 00:41:31,427 I don't know, Rabbi Hillel said something poignant. 680 00:41:32,637 --> 00:41:35,181 Universe always settles the score. 681 00:41:35,848 --> 00:41:38,434 - Does it? - No. 682 00:41:40,311 --> 00:41:41,729 But it should. 683 00:41:49,362 --> 00:41:53,366 Do you think you'll ever be able to look at him and not blame me? 684 00:41:54,242 --> 00:41:57,286 Yeah. Will you? 685 00:42:27,066 --> 00:42:28,276 (KNOCKING AT DOOR) 686 00:42:49,338 --> 00:42:50,506 PAULA: I'm Paula. 687 00:42:50,840 --> 00:42:53,342 - Hey, Paula. - How you doing? 688 00:42:55,011 --> 00:42:58,055 You work over at the college, or are you full-time over at the... 689 00:42:58,181 --> 00:43:00,474 I'm looking for a distraction. 690 00:43:01,184 --> 00:43:04,061 You don't need to talk to do that, do you?